Priming the ASTEPRO 0.15% Bottle

Before you use ASTEPRO 0.15% for the first time, you need to prime the bottle.

To prime:

  1. Remove the blue dust cover over the tip of the bottle and the blue safety clip just under the “shoulders” of the bottle.
  2. Hold the bottle upright with two fingers on the shoulders of the spray pump unit and put your thumb on the bottom of the bottle. Press upward with your thumb and release for the pumping action. Repeat this until you see a fine mist (6 sprays or less). Now your pump is primed and ready to use.
  3. To get a fine mist you must pump the spray fast and use firm pressure against the bottom of the bottle. If you see a stream of liquid, the spray will not work right and may cause nasal discomfort.
  4. If you do not use ASTEPRO 0.15% Nasal Spray for 3 or more days, you will need to prime the pump with 2 sprays or until you see a fine mist. If you do not see a fine mist, clean the tip of the spray nozzle.
 

Indication

ASTEPRO® (azelastine HCl) Nasal Spray 0.15% is indicated for the relief of the symptoms of seasonal and perennial allergic rhinitis in patients 12 years of age and older.

Important Risk Information

  • Avoid engaging in hazardous occupations requiring complete mental alertness when taking ASTEPRO Nasal Spray 0.15%
  • Avoid concurrent use of alcohol or other central nervous system depressants with ASTEPRO Nasal Spray 0.15%
  • In clinical studies, the most commonly reported adverse reactions, when dosed at 2 sprays per nostril once or twice daily, respectively, included bitter taste (4%, 6%), nasal discomfort (4%, 3%), epistaxis (2%, 1%), and sneezing (1%, 2%)
  • Pregnancy Category C: Based on animal data, may cause fetal harm
    Please see full Prescribing Information
    You are encouraged to report negative side effects of prescription drugs to the FDA.
    Visit www.fda.gov/medwatch, or call 1‐800‐FDA‐1088